The present study is focused to find out the “Effect of music on social skills among children with Intellectual Disability having Autism”. In this study 8 samples were selected based on the set criteria which were divided into experimental and control group, 4 in each group within age group of 7-12 years with intellectual disability having autism attending at Special Education Center, Secunderabad. A pre-test, post-test was used for the study. Statistical treatment of data was done by using mean (Mann Whitney u test) and (Wilcox signed rank test).The findings revealed that the post test score of both experimental and control group is higher than the pre-test score however, the experimental group performed better in post-test comparative to the post test of control group.

Type 2 diabetes mellitus (T2DM) is linked to skeletal problems, such as a higher risk of fractures. This skeletal fragility could be caused by a lack of blood supply and bone strength. Exenatide, a glucagon-like peptide-1 receptor agonist, was demonstrated to increase bone morphology and strength in T2DM mice over time by increasing blood supply to the bone and thereby encouraging bone production. The goal of this study is to see if geraniin has any preventive or therapeutic effects in albino rats that have been given exenatide and have been given diabetes. Streptozotocin was used to induce diabetes. Diabetic rats were given either Exenatide (3g/kg/day) or geraniin (40mg/kg) alone or in combination for eight weeks. BMD of the femur and lumbar vertebrae was assessed by dual-energy X-ray absorptiometry at the end of the trial (DXA). Serum glucose and glycosylated haemoglobin serum were also tested. Exenatide and geraniin, alone and in combination, reduced elevated blood glucose levels substantially. Exenatide medication significantly lowered HBA1C levels as compared to the positive control. The combination of geraniin and Exenatide significantly decreased blood glucose and HBA1C levels. In the femur and lumbar vertebrae, exenatide had little effect on BMD, whereas geraniin treatment greatly improved these results. This research implies that combining geraniin with exenatide may have a preventive and therapeutic role in the treatment of diabetic osteoporosis.

In this study, albino mice were used to test the wound healing ability of a gel made from hydro alcoholic extracts of Calendula officinalis (CE) and β-glucans in an excision wound model. The treated animals showed a considerable reduction in the time it took for epithelization and wound contraction in excision wound models, as well as rapid wound healing activity in a mixed gel. It's possible that this is related to synergism. The improved wound healing activity of hydro alcoholic extracts may be related to free radical scavenging action and phytoconstituents found in it, which, either alone or in combination, speed up the wound healing process.

The current pharmacological diabetic medications have a number of negative side effects. Herbal medication is in high demand for this chronic illness since it has fewer side effects and is more effective. As a result, the current study looked at the effects of Achyranthes bidentata (AB) root extract on bone properties in diabetic rats. In a rat model of osteoporosis, Achyranthes bidentata was shown to be beneficial. However, it is uncertain if Achyranthes bidentata can prevent osteoporosis in diabetics. The effects of Achyranthes bidentata on bone oxidative stress and turnover markers in diabetic rats were examined in this study.  Streptozotocin was used to cause diabetes (STZ). Diabetic Sprague-Dawley rats (n = 6) were administered either saline (control), metformin (1000mg/kg bwt), or Achyranthes bidentata (100mg/kg bwt) by gavage for 8 weeks. A healthy rat group was employed as a standard control group. Insulin, oxidative stress and bone turnover markers were measured in the blood using ELISA assays. Insulin and osteocalcin levels were significantly greater in diabetic rats administered AB than in diabetic control rats. Achyranthes bidentata may be able to prevent diabetic osteoporosis by boosting osteogenesis and lowering bone oxidative stress. The use of Achyranthes bidentata as an osteoporosis therapy in diabetic individuals is supported by these findings.

The effects and mechanism of Polygonum multiflorum Thunb water extract (PMT) on diabetes-related bone loss in rats were studied in this study. For 8 weeks, high-fat diet and streptozotocin induced diabetic rats were given Polygonum multiflorum Thunb (300mg/kg body weight) orally. Polygonum multiflorum Thunb increased the amounts of osteocalcin and BALP in the blood. Furthermore, Polygonum multiflorum Thunb enhanced femoral bone mineral density substantially. These findings show that Polygonum multiflorum Thunb may alleviate diabetes related bone problems via modulating osteoclast-related genes, implying that Polygonum multiflorum Thunb might be utilised to prevent diabetes-induced bone loss.